The Division of Biology & Biomedical Sciences. Washington University 660 South Euclid Avenue St. Louis, MO 63110; Room 740 Southwest Tower (office) McDonnell Genome Institute Room 5133 4444 Forest Park Parkway St. Louis, MO 63110 (lab) DBBS Profile; Lab Website Washington University - Cited by 22,434 . 2005-2013. A major research focus has been on how to avoid chemotherapy treatments, to limit the potential development of treatment-related . As being a first year student, he recognizes common problems and issues first year student . Computational Biology/Cancer Genomics Postdoctoral Scholar A postdoctoral scholar position in the area of Genomics and Bioinformatics is available in the Maher laboratory which is associated with The Genome Institute . Department of Radiation Oncology, Washington University in St. Louis - Cited by 1,631 - Bioinformatics - Cancer Genomics . Christopher Maher, PhD. Contact. Christopher Maher Environmental Specialist III at Missouri Department of Natural Resources St Charles, Missouri, United States 157 connections Zhang, Jin; Maher, Christopher A. J Zhang, E Mardis, C Maher. Researchers in Prof. Christopher Maher's research program (in conjunction with collaborator Ryan Fields) discovered that RAMS11 (RNA Associated with Metastasis 11), a novel long non-coding RNA, (i) promotes . Changes in DNA sequence alter transcription factor binding affinities and gene expression, and DNA methylation is an additional source of variation that is maintained throughout cellular division. sac@wustl.edu. The American Cancer Society awards Research Scholar Grants for researcher-initiated projects. Human and Statistical Genetics Faculty. . Director, The Genome Institute, Washington University in St. Louis. 2017-present. Room 11406, Mid-Campus Center (office) Date of Seminar. 314-286-1810 (fax) c.a.miller@wustl.edu; Division of Oncology Mail Stop 8007-0057-06 Washington University 660 South Euclid Avenue St. Louis, MO 63110; 6th Floor, Southwest Tower . 660 S. Euclid Ave., St. Louis, MO 63110-1010. Gene expression is driven by specific combinations of transcription factors binding to regulatory sequences to define cell type expression profiles. 2004-2005. AU - Jones, Caroline N. N1 - Funding Information: We would like to thank Carla Finkielstein for her thoughtful discussions on experimental design and RNA seq data analysis. Bioinformatics 33 (4), 555-557, 2017. By Christopher Maher, Published on 10/28/14. Department of Medicine, Asst. Open Menu . . In addition to Pradeep - Haley, Wenjia, Peter, Grace, Mark and Faridi contributed strongly to this nice manuscript showcasing our technology EnhanceAR-Seq for cell-free DNA analysis in metastatic . Assistant Professor. Department of Obstetrics & Gynecology. AU - Maher, Christopher A. Impressive effort led by Pradeep in our lab, collaborating with Ha Dang in Chris Maher's lab, and the clinical prowess of Russell Pachynski. Christopher A. Maher, PhD, assistant professor of medicine at Washington University School of Medicine in St. Louis, has received a three-year, $450,000 Susan G. Komen Career Catalyst Award for research focused on understanding the role of long noncoding RNAs in estrogen-positive breast cancer treatment resistance. Nature 458 (7234), 97-101, 2009. 2022 Washington University in St. Louis Skip to content Skip to search Skip to footer. By Christopher Maher, Published on 12/07/16. 314-286-1800. mgi@wustl.edu Shown is a scan of a patient with prostate cancer and (in color) a 3-D rendering of the prostate and tumor. To narrow your search for students, please use one of the tools below: Student by Programs Biochemistry, Biophysics, and Structural Biology Biomedical Engineering Biomedical Informatics and Data Science Cancer Biology Computational and Systems Biology Developmental, Regenerative and Stem Cell Biology Human and Statistical . Open Menu . Help & FAQ; Home; Profiles; Departments, Divisions and Centers; Research output; Search by expertise, name or affiliation. . 314-747-7402 (office) 314-747-5123 (fax) bkahl@wustl.edu; Division of Oncology Mail Stop 8056-0029-11 Washington University 660 South Euclid Avenue Department of Medicine, Asst. Division of Biology and Biomedical Sciences; Institute of Clinical and Translational . MSTP Student Search. Joy Zalis Kiefer, Director of Undergraduate Research and Associate Dean in the College of Arts & Sciences; Jane Green and Stacy Ross, Editors; Kristin G. Sobotka, Undergraduate Research Coordinator. Post Address: MSC 8064-37-1005, 660 S. Euclid Ave. St. Louis, MO 63110 St. Louis, MO 63110. Defining the mechanism and therapeutic targets of lncRNAs in castration resistant prostate cancer . Christopher A. Maher, PhD, an assistant professor of medicine at Washington University School of Medicine and a Siteman Cancer Center research member, has received the William C. Rippe Award for Distinguished Research in Lung Cancer.. Introduction. However, these strategies. Christopher Maher, PhD. Contact. Non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, epigenetics, cancer. Contact. Research Technician For all positions review of applications will begin immediately and will continue until the positions are filled. Professor Emerita. Hematology Division The Maher laboratory (www.maherlab.com) at Washington University integrates computational and experimental techniques to study cancer. Christopher A. Maher. The dates for the 2022-2023 program are September 1, 2022 - June 30, 2023. Christopher A. Maher Existing small noncoding RNA analysis tools are optimized for processing short sequencing reads (17-35 nucleotides) to monitor microRNA expression. Washington University Division of Biology and Biomedical Sciences MSC 8226-13-04 660 S. Euclid Ave. St. Louis, MO 63110-1093 Prospective Students Mahal is a PhD student in the Evolution, Ecology & Population Biology program. Defining the mechanism and therapeutic targets of lncRNAs in castration resistant prostate cancer Therefore, our lab is dedicated to the discovery and characterization of novel lncRNAs, elucidating lncRNA functionality, and assess their clinical applicability. Arts & Sciences. Follicular lymphoma (FL) is the most common indolent non-Hodgkin's lymphoma; however, it remains incurable with conventional therapies and is poorly responsive to checkpoint blockade. Cancers (Basel). 314-286-0263 (office) 314-286-1810 (fax) c.a.miller@wustl.edu; Division of Oncology Mail Stop 8007-0057-06 Washington University 660 South Euclid Avenue Washington University 660 South Euclid Avenue St. Louis, MO 63110; 6th Floor, Southwest Tower (office) . Christopher A. Maher, PhD, an assistant professor of medicine at Washington University School of Medicine and a Siteman Cancer Center research member, has received the William C. Rippe Award for Distinguished Research in Lung Cancer. Christopher Maher, associate professor, Oncology Division, Stem Cell Biology, . Washington University. LEAP is supported by Washington University in St. Louis' Institute of Clinical and Translational Sciences, Siteman Cancer Center, Skandalaris Center for Interdisciplinary Innovation and Entrepreneurship, Center for Drug Discovery, and Office of Technology . . 314-286-0263 (office) 314-286-1810 (fax) c.a.miller@wustl.edu; Division of Oncology Mail Stop 8007-0057-06 Washington University 660 South Euclid Avenue Room 740 Southwest Tower (office) McDonnell Genome Institute. Our community includes recognized innovators in science, medical education, health care policy and . To apply, please send a CV, including a list of three references, to Dr. Christopher Maher (christophermaher at wustl dot edu). Access Restrictions. 314-286-2856 (office) christophermaher@wustl.edu. Contact. Christopher Maher Associate Professor of Medicine Section of Stem Cell Biology Division of Biology and Biomedical Sciences Section of Bone Marrow Transplant & Leukemia Institute of Clinical and Translational Sciences Siteman Cancer Center 19587 Citations 2001 2022 Research activity per year Overview Fingerprint Network Research output (97) All students participating in the OGR Extensive Study program will take part in cutting-edge research as part of an independent research team in a lab . . The Maher laboratory at Washington University integrates computational experimental techniques to study cancer. Washington University School of Medicine. Transcription occurs across more than 70% of the human genome and more than half of currently annotated genes produce functional noncoding RNAs. Washington University School of Medicine. Director, The Genome Institute, Washington University in St. Louis. CA Maher, C Kumar-Sinha, X Cao, S Kalyana-Sundaram, B Han, X Jing, . McDonnell Genome Institute (MGI) Washington University School of Medicine. He is currently investigating the role of circular RNAs in the context of colorectal cancers. . 2013. Methods in Molecular Biology. John P. Atkinson, M.D. Washington University School of Medicine 660 S. Euclid Ave., St. Louis, MO 63110-1010 Consistently ranked a top medical school for research, Washington University School of Medicine is also a catalyst in the St. Louis biotech and startup scene. Recipients must be in the first six years of an independent research career or faculty . Christopher Maher, PhD Assistant Professor of Medicine Email: christophermaher@wustl.edu Washington University in St. Louis (WU) Our research focuses integrative cancer biology research for the purpose of translating genome-based knowledge into novel diagnostic, prognostic, therapeutic strategies in cancer research. Associate Professor of Medicine, Division of Oncology, Section of Molecular Oncology, Washington University School of Medicine Research Interest Translating genome-based knowledge through integrative analysis of high-throughput genomic technologies into the development of novel diagnostic, prognostic and therapeutic strategies in cancer. I received my PhD in Department of Computer Science & Engineering at University of Connecticut under Dr. Yufeng Wu. Stem Cell Biology. Genomics, Transcriptomics, Bioinformatics, Cancer Technologies, Computational Biology, non-coding RNA, Systems Biology . To apply, please send a CV, including a list of three references, to Dr. Christopher Maher (christophermaher at wustl dot edu). Cancer scientists Ryan C. Fields, MD, the Kim and Tim Eberlein Distinguished Professor and chief of the Section of Surgical Oncology at the School of Medicine, and Christopher A. Maher, an associate professor of medicine and assistant director of the McDonnell Genome Institute at the School of Medicine, received a $2.8 million R01 grant from the National Cancer Institute (NCI) of the National . 12-7-2016. 314-362-8828 (lab) bd@wustl.edu; Division of Hematology Mail Stop 8125-0020-08 Washington University 660 South Euclid Avenue St. Louis, MO 63110 The level of a specific molecule present in prostate tumors is an indicator of whether the cancer is aggressive and likely to spread, according to new research from Washington University School of Medicine in St. Louis. Division of Oncology. Sid Puram, M.D., Ph.D. - Understanding the role of tumor heterogeneity in cancer biology, including its contributions to cancer development, growth, metastasis, and treatment resistance mechanisms, in order to translate these insights into new diagnostics and novel therapeutics. Researchers in Prof. Christopher Maher's research program (in conjunction with collaborator Ryan Fields) discovered that RAMS11 (RNA Associated with Metastasis 11), a novel long non-coding RNA, (i) promotes metastatic disease, (ii) confers resistance to topoisomerase i Liquid biopsy assay for personalized prostate cancer treatment SV-HotSpot Manual Installation. Of these transcripts, the majority-long . Clone the SV-Hotspot repository (with PATH_TO_SV_HOTSPOT is the local directory where you want to install SV-HotSpot): Washington University in St. Louis McKelvey School of Engineering MSC: 1097202190 1 Brookings Drive St. Louis, MO 63130-4899 Phone: 314-935-7208 bme@wustl.edu Contact Us. Christopher Maher - Medical Oncology. Consistently ranked a top medical school for research, Washington University School of Medicine is also a catalyst in the St. Louis biotech and startup scene. By Christopher Maher, Published on 12/07/16. Articles Cited by Public access. c.salvador@wustl.edu. Bioinformatics; Cancer genomics; . Contact. Department of Medicine. Campus Box 8501. Associate Professor of Medicine and Genetics, Washington University School of Medicine, St. Louis, MO. Arts & Sciences. Instructor of Medicine, Washington University School of Medicine, St. Louis, MO. Non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, epigenetics, cancer. Bio 200/500 Undergraduate Independent Research. jaehyung.cho@wustl.edu; Division of Hematology Mail Stop 8125-0020-08 Washington University 660 South Euclid Avenue St. Louis, MO 63110; Room 8804A, Clinical Sciences Research Building (office) Room 8804/8808, Clinical Sciences Research Building (lab) Lab website Arts & Sciences. Contact. Christopher A. Maher, PhD. 41-68 (Methods in Molecular Biology). Date of Seminar. Christopher Maher, Washington University School of Medicine in St. Louis. AU - Lawrence, Christopher B. 2022 Washington University in St. Louis Skip to content Skip to search Skip to footer. Maher's lead mentor is Elaine R. Mardis, PhD, the Robert E. and Louise F. Dunn . MSC 8226-13-04 660 S. Euclid Ave. St. Louis, MO 63110-1093 Prospective Students Prospective Students Christopher Maher, Ph.D. Back to Directory Print Update Profile Associate Professor Internal Medicine Medical Oncology Cancer Biology Program Computational and Systems Biology Program Molecular Genetics and Genomics Program Research Profiles at Washington University School of Medicine Home. There are 300+ professionals named "Christopher Maher", who use LinkedIn to exchange information, ideas, and opportunities. 314-747-1171 (office) a.rohatgi@wustl.edu; Division of Oncology Mail Stop 8056-0029-11 Washington University 660 South Euclid Avenue St. Louis, MO 63110 Maher CA, Ding L, Ley TJ, Mardis ER, Wilson RK BMC Genomics 2016 Nov 7;17(1):880; Our diverse and interdisciplinary team enables us to focus on translating genome based discoveries into the clinic. Patrick A DeSouza 1 2, Xuan Qu 1, Hao Chen 1 3, Bhuvic Patel, Christopher A Maher, Albert H Kim. Verified email at wustl.edu - Homepage. Published by the Office of Undergraduate Research. 314-273-0286 (office) 314-362-1953 (fax) christopherm@wustl.edu; Division of Oncology Mail Stop 8007-0057-07 Washington University 660 South Euclid Avenue Open Menu. Oncology Division. 71: 2017: "More immediately, the new information could help doctors . 2013. Dr. Herzog is interested in how the tumor microenvironment (TME) impacts the progression and response to therapy in lung cancer. Christopher Maher, PhD. Christopher A. Maher Washington University Verified email at wustl.edu. Given by the Lung Cancer Research Foundation, the annual award goes to an "investigator whose proposal not only demonstrates exceptional scientific merit but . St. Louis, MO 63110. 2013-2017. Computational Biology/Cancer Genomics Postdoctoral Scholar Title. 660 South Euclid Avenue. Home; Search; Browse Collections; My Account; About; Digital Commons Network . Research Interests. Genomic landscape of cancer. Department of Medicine | Department of Biochemistry & Molecular Biophysics. 2022 Washington University in St. Louis Skip to content Skip to search Skip to footer. - Complement activation and regulation in innate and adaptive immunity. Humana Press Inc., 2020. pp. Christopher Maher, Washington University School of Medicine in St. Louis. Long non-coding RNA as cancer biomarker and drug target. 4240 Duncan Ave. Suite 110 St Louis, MO 63130 314-747-1794 otm@wustl.edu Meet the Team Publications of Christopher A. Miller, PhD, Assistant Professor in the Oncology Division, Washington University in St. Louis. Email: mbugay@wustl.edu. FL arises from B-lymphocytes and develops slowly (and often asymptomatically). by | Nov 12, 2021 | Cabanski, Christopher, Fields, Ryan, Maher, Christopher, Silva-Fisher, Jessica Technology Description . Non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, epigenetics, cancer. Page of 1. "This study could aid the search for better therapies to treat aggressive prostate cancer," said co-senior author Christopher A. Maher, PhD, an associate professor of medicine and an assistant director at The McDonnell Genome Institute at Washington University School of Medicine. I am present a postdoctoral research associate under Dr. Christopher Maher at Washington University in St. Louis. Cancer scientists Ryan C. Fields, MD, the Kim and Tim Eberlein Distinguished Professor and chief of the Section of Surgical Oncology at the School of Medicine, and Christopher A. Maher, an associate professor of medicine and assistant director of the McDonnell Genome Institute at the School of Medicine, received a $2.8 million R01 grant from the National Cancer Institute (NCI) of the National . Robert H. Allen, MD. Office of Technology Management. Bio 200/500 Undergraduate Independent Research. Washington University. A postdoctoral scholar position in the area of Genomics and Bioinformatics is available in the laboratory of Dr. Christopher Maher at The McDonnell Genome Institute at Washington University School of Medicine in St. Louis. Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast Christopher A. Maher, Washington University School of Medicine in St. Louis et al Journal npj Breast Cancer Publication Date 2017 Volume 3 Document Type Open Access Publication DOI 10.1038/s41523-017-0048- Rights and Permissions My name is Jin Zhang. Recent advances in immune-based therapy have improved outcomes for many lung cancer . Applications for the 2022-2023 program are now closed but will reopen for the 2023-2024 program in November of 2022. Hung is a Cancer Biology student and in Dr. Christopher Maher lab. Christopher A. Maher, PhD, an assistant professor of medicine at Washington University School of Medicine in St. Louis, has received a four-year, $792,000 Research Scholar Grant from the American Cancer Society.. Read More. Arpana Agrawal, Ph.D. - Genetic and environment studies of addictions. From the Washington University Senior Honors Thesis Abstracts (WUSHTA), Volume 6, Spring 2014. Division of Oncology. Washington University 660 South Euclid Avenue St. Louis, MO 63110; 1418 Cross Street Suite 180 Shiloh, IL 62269 (office) Research. Washington University School of Medicine Digital Commons@Becker Open Access Publications 2014 Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC Kaihua Zhang Washington University School of Medicine in St. Louis Lamont Jones Washington University School of Medicine in St. Louis Home; Search; Browse Collections; My Account; About; Digital Commons Network . Please send a CV and a list of three references, to Dr. Christopher Maher (christophermaher . SV-HotSpot is developed at Christopher Maher Lab at Washington University in St. Louis. Lee Ratner, M.D., Ph.D. - Molecular biology and pathogenesis of . Christopher A. Maher, PhD. Abstract. 10-28-2014. By Christopher Maher, Published on 10/28/14. April 15, 1938 - January 22, 2021 Associate Professor (1972-1977) Department of Medicine. To narrow your search for students, please use one of the tools below: Students by Program Biochemistry Biochemistry, Biophysics, and Structural Biology Biomedical Informatics and Data Science Cancer Biology Computational and Molecular Biophysics Computational and Systems Biology Developmental, Regenerative and Stem Cell Biology Evolution . 2021 Mar 31;13(7):1604. A blood test developed at Washington University School of Medicine in St. Louis could help determine next steps for patients whose prostate cancer has - Siteman Cancer Center. She works in the lab of Dr. Rachel Penczykowski, where she studies (1) how urbanization alters soil abiotic and biotic properties and (2) the consequences of these altered properties on plant communities. Katherine Parker Ponder, MD. / Gene Fusion Discovery with INTEGRATE. Christopher J. Maher, Elaine R. Mardis. Assistant Professor of Medicine and Genetics, Washington University School of Medicine, St. Louis, MO. Chaudhuri shares senior authorship with Christopher Maher, PhD, an associate professor of medicine and assistant director of the McDonnell Genome Institute, . Mentor: Christopher Maher Campus Box 8069. Facebook; Twitter; Instagram 2022 Washington University in St. Louis . 660 South Euclid Avenue. Research Profiles at Washington University School of Medicine Home. HOME | chrismaherlab Welcome to the Maher Lab Long intergenic non-coding RNAs (lncRNAs) represent an emerging and under-studied class of transcripts with critical roles in human cancers. 4444 Forest Park Ave. St. Louis, MO 63108. Access Restrictions. Christopher A. Maher Colorectal cancer (CRC) is the most common gastrointestinal malignancy in the U.S.A. and approximately 50% of patients develop metastatic disease (mCRC). Washington University School of Medicine in St. Louis, +3 more. Help & FAQ; Home; Profiles; Departments, Divisions and Centers; Research output; .